Human osteosarcoma SJSA1
“An osteosarcoma (OS) or osteogenic sarcoma (OGS) (or simply bone cancer) is a cancerous tumor in a bone. Specifically, it is an aggressive malignant neoplasm that arises from primitive transformed cells of mesenchymal origin (and thus a sarcoma) and that exhibits osteoblastic differentiation and produces malignant osteoid.[1]
Osteosarcoma is the most common histological form of primary bone sarcoma.[2] It is most prevalent in teenagers and young adults.[3]”
Source : Wikipedia
Visual Phenotype
1 Day Post Engraftment
Notes
Cells get stuck at the injection site due to cell intrinsic mechanisms. GFP is better tolerated by the cells than tdTomato (when driven from a similar casette)