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Phenotypes of human cancer xenografts in zebrafish

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Xenografts

B6BmSc2 derived syngeneic murine osteosarcoma

Sarcoma | Osteosarcoma

B6BmSc2 derived syngeneic murine osteosarcoma, derived from automatically transformed bone marrow derived murine mesenchymal stem cells (high passage = 50+), due to its origin (Black 6 mice) it can be used to generate syngrafts in Bl6 mice for further validation in more complex vertebrate models. Continue reading B6BmSc2 derived syngeneic murine osteosarcoma

U2OS Human osteosarcoma

Sarcoma | Osteosarcoma

Human osteosarcoma U2OS Continue reading U2OS Human osteosarcoma

4T1 Murine mammary carcinoma (TNBC)

Mammary carcinoma | Triple negative

Murine mammary carcinoma 4T1 Continue reading 4T1 Murine mammary carcinoma (TNBC)

SJSA1 Human osteosarcoma

Sarcoma | Osteosarcoma

Human osteosarcoma SJSA1 Continue reading SJSA1 Human osteosarcoma

HOS143b Human osteosarcoma

osteosarcoma

Human Osteosarcoma cell line HOS143b Continue reading HOS143b Human osteosarcoma

MDA-MB231B1 Triple Negative Breast Cancer (bone tropic)

Breast Cancer | Triple Negative

Between 10-20% of the human breast cancers are considered Triple Negative Breast Cancer (TNBC), which means that the tumour cells do not express the receptors for estrogen, progesterone, and Her2. In practice, that means that anticancer drugs that target these receptors or hormone therapy will not be effective. Continue reading MDA-MB231B1 Triple Negative Breast Cancer (bone tropic)

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